Yeah this time you should reboot first... specially before you make posts here... as we assume you have done all kind of basic noob stuff like rebooting BEFORE posting.
If I have understood right your now talking of removable drive, if nothing else works try opening its case, removing HD, plug it straight to comp and see if that works. That can narrow it down where problem is.
If drive works on comp but not after you plug it back to its casing = casing fault, if it still doesnt work on both cases = HD prob.